Hi Geoff, I can't say that I've made much progress in tracing Timothy Kane back to Ireland. One of the bigger issues is that I can't be certain of Timothy's mother's maiden name. I'm guessing that it may have been Murphy, given that Timothy lived with a Murphy family when he first arrived in Massachusetts in the 1850s (Daniel and Ellen Murphy). Also, Timothy and his wife Catherine (Hayes) are listed in the 1860 US Census for Holliston, MA as sharing the same dwelling number as Philip and Susan Murphy. I was able to confirm the existence of a baptismal record for a Timy Cain from July 1835 that took place in the Roman Catholic parish of Caheragh in the diocese of Cork & Ross. His parents, John Cain and Catherine Murphy, were living in Rerahinagh at the time of his birth. The sponsers were Joseph Murphy and Ellen Cain. John and Catherine appear to have had another child (Jos?) in 1839. He was also baptised in Caheragh, and the sponsers were Patrick and Ellen Murphy. There is a record of the marriage of a John Keane and Catherine Murphy from 28 February 1835 in the parish of Drimoleague & Drinagh in the diocese of Cork & Ross. At the time of the marriage, John Keane was living in Cahara and Catherine Murphy's home parish may have been Drimoleauge. Both John and Catherine were listed as servants, and the marriage was witnessed by Michl. Murphy and Timy. Keane. County Cork is certainly the ancestral home for the Keane/Cain/Kane family, but there are still a lot of gaps left to fill before any of Timothy's past in Ireland can be confirmed. I've not had much success using DNA to uncover any additional Kane leads to this point. I haven't found much information about Mary Sweeney, the spouse of Timothy E Kane (and I'm guessing your grandmother). Her death certifcate indicated she was born in Charlestown, MA to John Sweeney and Mary McHugh (McHue?) but that trail also goes cold quickly. I wish I had more information to share. Have a great trip to Ireland. It's been a couple of years since I was last there, but I haven't yet made it to the areas where the Kane family may have lived. I see that you have come across my mother Beverly's family tree; I also have a family tree on Ancestry.com that is pubically viewable. Let me know if I can be of further help. Thanks, Johnhttps://www.ancestry.com/family-tree/tree/52159322/family/familyview?cfpid=13310087309&fpid=342070156878&usePUBJs=true