Looking for information on John Collins and Mary Witherow

I am looking for any information on John Collins born abt 1800 and died in Cavan Ireland Mar. 1878 and Mary Witherow born abt 1801 and died Dec. 9 1861 in Ireland.  I am trying to find information related to a possible connection to Alexander Smyth or Mary Lyons from Tyrone NI

Thanks, Ruth